师资力量

Resume

Received a Ph.D. from Emory University in the United States, followed by postdoctoral training at Genentech, Inc. in the United States.

Research Areas

The microtubule cytoskeleton plays a crucial role in numerous cellular activities, including cell division and cell motility, which are essential for the growth, development, and reproduction of organisms. Microtubules, in combination with various protein complexes, form intricate and specialized cellular structures such as centrioles, spindle fibers, and cilia, exhibiting behaviors that are both perplexing and fascinating. Our research group employs cutting-edge, interdisciplinary technologies to focus on the dynamic structure and function of microtubules in cellular processes, organ development, and human diseases.

Selected Publications

  1.   Liu Y, Yan S, Wang J, Dong D, Yan S, Yin H, Liu K, Liu M, Liu H, Li D, Gao J, Xie W, Zhou J. The parkin-γ-tubulin axis regulates epidermal homeostasis and is associated with the susceptibility to psoriasis. Cell Death Differ. 2026; doi: 10.1038/s41418-026-01693-x.

  2.    Sun S, Wang Z, Xu Z, Wang Z, Sun J, Li K, Liu M, Zhao H, Liu P, Zhou J. CFAP100 couples microtubule glutamylation to spindle pole integrity in keratinocytes to promote epidermal development. Nat. Commun. 2025; 16:5591.

  3.    Tan Y, Huang Z, Jin Y, Wang J, Fan H, Liu Y, Zhang L, Wu Y, Liu P, Li T, Ran J, Tian H, Lam SM, Liu M, Zhou J, Yang Y. Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in male mice. Nat Commun. 2024; 15(1):8273.

  4.    Zhong T, Wu X, Xie W, Luo X, Song T, Sun S, Luo Y, Li D, Liu M, Xie S, Zhou J. ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes. Cell Death Differ. 2022; 29(9):1719-1729.

  5.    Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y, Yang Y, Yu F, Guo H, Zhang L, Xie S, Li D, Gao J, Zhang X, Zhu X, Zhou J. ASK1-mediated phosphorylation blocks HDAC6 ubiquitination and degradation to drive the disassembly of photoreceptor connecting cilia. Dev Cell. 2020; 53(3):287-299.

E-mail:junzhou@sdnu.edu.cn

Office addr:College of Life Sciences, Shandong Normal University