Resume
2013-Present, College of Life Sciences, Shandong Normal University, Associate Professor
2009-2012, College of Life Sciences, Shandong Normal University, Instructor
2006-2009, Shandong Normal University, Ph.D.
2003-2006, Shandong Normal University, M.S.
1999-2003, Yantai Normal University, B.S.
Research Areas
We focused on some modern diseases such as tumors, obesity and cardiovascular diseases, using mice as experimental animal models to carry out research on the pathogenesis of the above diseases.
1. The mechanism of reversible translational modification of important proteins in tumor, obesity and cardiovascular disease.
2. The mechanism of exosomes-mediated cell-cell communication in tumor, obesity and cardiovascular disease.
Projects:
1. National Natural Science Foundation of China（31871441）, Interation of P49/STRAP and MYOCD regulates phenotypic switching of vascular smooth muscle cells synergistically, 2019.01-2022.12
2. Shandong Natural Science Foundation (ZR2017MH087）, The mechanism of SRFBP1 inhibiting the phenotype transition of vascular smooth muscle cells, 2017.06-2020.12
3. National Natural Science Foundation of China (81100193), The mechanism of microRNA in macrophage foam cell-derived exosomes promotes the proliferation of vascular smooth muscle cells. 2012.01-2014.12
4. Special Scientific Research Fund for Doctoral Programs of Higher Education Institutions of the Ministry of Education (20113704120006), The mechanism of TNFα in the reverse transport of macrophage-derived cholesterol. 2012.01-2015.12
5. Shandong Province Outstanding Young and Middle-aged Scientists Research Award Fund (BS2013YY043), The mechanism of miRNA-181a in PDGF-BB-induced vascular smooth muscle cell proliferation and migration. 2013.10-2016.10.
Key words:Protein translational modifications, Cancer, Obesity, Cardiovascular disease, exosomes, cell communication
Honors and Awards
1. Outstanding Scientific Research Achievement Award of Higher Education Institutions of Shandong Province (Natural Science Category), Third Prize
2. Excellent teaching award of Shandong Normal University
3. Excellent instructor of educational practice
Selected Publications
Zhang L,Yu L, Liu Y, Wang S, Hou Z, Zhou J.miR-21-5p promotes cell proliferation by targeting BCL11B in Thp-1 cells. Oncol Lett. 2021; 21(2):119.
Zhang L,Gao Z, Yu L, Zhang B, Wang J, Zhou J. Nucleotide-binding and oligomerization domain (NOD)-like receptors in teleost fish: Current knowledge and future perspectives. J Fish Dis. 2018; 41(9):1317-1330.
Zhang L,Zhang Y, Ye L, Pan J. Effect of polyunsaturated fatty acids on the metabolism of apoB100-containing lipoproteins in apolipoprotein E deficient mice. Prog Biochem Biophys. 2015; 42(9):843-849
Zhang L,Geng Y, Xiao N, Yin M, Ren G, Mao L, Zhang S, Pan J. Dietary low n-6/n-3 polyunsaturated fatty acid ratios decrease C-reactive protein expression in apolipoprotein E-null mice. Nutrition. 2010; 26:829-834.
Zhang L,Geng Y, Xiao N, Yin M, Mao L, Ren G, Zhang C, Liu P, Lu N, An L, Pan J. High dietary n-6/n-3 PUFA ratio promotes HDL cholesterol level, but does not suppress atherogenesis in apolipoprotein E-null mice. J Ather Throm. 2009; 16(4):463-471.
Group Members
Current Members:
Jing Cai, M.S. student（2019 class）
Xiao Liu, M.S. student（2020 class）
Yu Wang, M.S. student（2020 class）
Junru Qin, M.S. student（2021 class）
Miaomiao Zheng, M.S. student（2021 class）
Past Members:
Yanyan Zhang, M.S. student（2013 class）
Tingwei Li, M.S. student（2014 class）
Shasha Wang, (M.S. student（2014 class）
Bo Zhang, M.S. student（2015 class）
Li Yu, M.S. student（2016 class）)
Yiran Liu, M.S. student（2017 class）
Guoxiang Sun, M.S. student（2017 class）
Xiaolong Zhang, M.S. student（2018 class）
Zhenfeng Hou, M.S. student（2018 class）
E-mail：zhangliang@sdnu.edu.cn
Telephone：
Office addr：Room 553, College of Life Sciences, Shandong Normal University
