Resume
2018-Present, College of Life Sciences, Shandong Normal University, Instructor
2014-2018, Jilin University, Ph.D.
2012-2014, Jilin University, M.S.
2006-20012, Jilin University, B.S.
Research Areas
The outbreak of the new coronavirus (COVID-19) has caused a global pandemic, prompting people to pay attention to the harm and prevention of infectious diseases once again. There is currently no effective treatment. In recent years, PROTAC technology has received widespread attention from drug developers. This technology is different from the traditional small molecule inhibitor that inhibits the function of the target protein by binding to the active site of the target protein. degradation, so as to achieve the effect of disease treatment. In view of this new mode of action of PROTAC technology and many advantages compared with traditional small molecule inhibitors, it has a promising application in antiviral therapy. Currently studying how to use PROTAC technology to treat the new coronavirus.
Key words:new coronavirus; PROTAC; antivirus
Honors and Awards
N/A
Selected Publications
Pan W,Nie H, Wang H, He H. Entry of Bovine Parainfluenza Virus Type 3 into MDBK Cells Occurs via Clathrin-Mediated Endocytosis and Macropinocytosis in a acid-Dependent Manner. Veterinary microbiology.2021..
Pan W,Nie H, Wang H, He H. Bovine Parainfluenza Virus Type 3 (BPIV3) Enters HeLa Cells via Clathrin-Mediated Endocytosis in a Cholesterol- and Dynamin-Dependent Manner. Viruses. 2021 May 31;13(6):1035.
Pan W,Shen Z, Wang H, He H. The host cellular protein Ndufaf4 interacts with the vesicular stomatitis virus M protein and affects viral propagation. Virus Genes. 2021 Jun;57(3):250-257.
Pan W,Song D, He W, Lu H, Lan Y, Tong J, et al. The matrix protein of vesicular stomatitis virus inhibits host-directed transcription of target genes via interaction with the TFIIH subunit p8. Veterinary microbiology 2017;208:82-8.
Pan W,Song D, He W, Lu H, Lan Y, Li H, et al. EIF3i Affects VSV Growth by Interacting with Matrix Protein. Veterinary microbiology. 2017:212:59-66.
Yongping Wu，Yulan Jin，Wei Pan, Chengjin Ye，Xiaoyuan Sun，Yanting Sun ，Boli Hu,Jiyong Zhou. Comparative proteomics analysis of host cells infected with Brucella abortus A19.Electrophoresis 2014, 35, 1130–1143.
Zhao K, He W, Xie S, Song D, Lu H,Pan W, et al. Highly pathogenic fowlpox virus in cutaneously infected chickens, China. Emerging infectious diseases 2014;20:1208-10.
Group Members
Current Members:
Yaodong Xia, M.S. student（2020 class）
Past Members:
N/A
E-mail：panweisdnu@sdnu.edu.cn
Telephone：0531-86180921
Office addr：Room 550, College of Life Sciences, Shandong Normal University
