Resume
2020-Present, College of Life Sciences, Shandong Normal University, Instructor
2014-2020, Huazhong Agricultural University, Ph.D.
2010-2014, Liaocheng University, B.S.
Research Areas
Atherosclerosis is the main cause of coronary heart disease, cerebral infarction, and peripheral vascular disease. Vascular endothelial cell dysfunction is an important hallmark of atherosclerosis, which is manifested by abnormal endothelial cell arrangement and cell gap, decreased osmotic pressure. Cilia plays an important role in regulating vascular endothelial cell function; however, its dynamic changes and regulatory mechanism are still unclear. Our research group focuses on the role of cilia and related signaling pathways in the development of atherosclerosis.
Key words: Cilia; Signal transduction; Atherosclerosis; Vascular endothelium
Honors and Awards
Guide undergraduates to award excellent graduation thesis of Shandong Normal University
Selected Publications
Tan, Yanjie; Jin, Yi; Zhao, Pengxiang; Wu, Jian; Ren, Zhuqing. Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament. Cell Death & Disease, 2021, 12(12): 0-1102.
Tan Y, Jin Y, Wang Q, Huang J, Wu X, Ren Z. Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells. Cells. 2019 Oct 11;8(10):1241. doi: 10.3390/cells8101241.
Tan Y, Ma Z, Jin Y, Zong R, Wu J, Ren Z. MicroRNA 4651 regulates nonsense-mediated mRNA decay by targeting SMG9 mRNA. Gene. 2019 Jun 15;701:65-71. doi: 10.1016/j.gene.2019.03.031. Epub 2019 Mar 19.
Tan Y, Jin Y, Wu X, Ren Z. PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism. BMC Mol Biol. 2019 Nov 8;20(1):24. doi: 10.1186/s12867-019-0141-z
Tan Y, Jin Y, Wang S, Cao J, Ren Z. The RNA surveillance factor UPF1 regulates the migration and adhesion of porcine skeletal muscle satellite cells. J Muscle Res Cell Motil. 2021 Jun;42(2):203-217. doi: 10.1007/s10974-020-09585-4.PMID: 32990898
Jin Y,Tan Y, Chen L, Liu Y, Ren Z. Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression. Int J Mol Sci. 2018 Nov 2;19(11):3445. doi: 10.3390/ijms19113445.
Jin Y, Ren Z,Tan Y, Zhao P, Wu J. Motility Plays an Important Role in the Lifetime of Mammalian Lipid Droplets. Int J Mol Sci. 2021 Apr 7;22(8):3802. doi: 10.3390/ijms22083802.
Jin Y,Tan Y, Zhao P, Ren Z. SEIPIN: A Key Factor for Nuclear Lipid Droplet Generation and Lipid Homeostasis. Int J Mol Sci. 2020 Nov 2;21(21):8208. doi: 10.3390/ijms21218208.
Zhao P, Jin Y, Wu X, Huang J, Chen L,Tan Y, Yuan H, Wu J, Ren Z. Artificial Lipid Droplets: Novel Effective Biomaterials to Protect Cells against Oxidative Stress and Lipotoxicity. Nanomaterials (Basel). 2022 Feb 17;12(4):672. doi: 10.3390/nano12040672.
He N, Ma D,Tan Y, Liu M. Upregulation of O-GlcNAc transferase is involved in the pathogenesis of acute myeloid leukemia. Asia Pac J Clin Oncol. 2021 Nov 24. doi: 10.1111/ajco.13685.
Group Members
Current Members:
Zhenzhou Huang, M.S. student（2020 class）
Jiaying Wang, M.S. student（2021 class）
Past Members:
N/A
E-mail：620036@sdnu.edu.cn
Telephone：
Office addr：Room 551, College of Life Sciences, Shandong Normal University
